Ivosidenib is under clinical development by Les Laboratoires Servier and currently ... advanced hematological malignancies including relapsed/primary refractory acute myeloid leukemia (AML), advanced ...

Diffuse midline gliomas (DMG) with histone H3 lysine27-to-methionine mutations (H3K27M glioma) represent a highly aggressive subtype of glioma, which predominantly arise in children and young adults ...