This developmental plasticity requires a strict temporal and spatial control of the cell cycle. Cell-cycle activation in quiescent cells is correlated with a change in chromatin structure and ...

Understanding the dynamics and stability of these marks through the cell cycle is crucial in maintaining a given chromatin state. Recent research has highlighted DNA methylation as a bona fide ...

This study presents fundamental insights into overcoming resistance in hormone receptor-positive breast cancer by demonstrating that sustained CDK4/6 inhibitor treatment, either alone or in ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

We revealed that, compared to those patients who survived longer than five days, PMNs from patients who had fulminant sepsis were characterized by a dysfunctional hyper-activation, show altered ...

Dow Jones industrial giant Caterpillar is approaching a fresh buy point ahead of fourth-quarter earnings results.

Jan. 28, 2025 — A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood.

Jan. 28, 2025 — A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood.

Nagayama, K. and Hirooka, Y. (2025) Changes in the Mechanical Environment of the Nucleus with Cell Crowding and Its Effects on DNA Damage Resistance. Journal of Biosciences and Medicines, 13, 230-242.

Paper mills’ are contaminating the world’s scholarly output with fake papers that hinder research. Lifesaving biomedical ...

Extended cash runway into late 2027, beyond a potentially registration-enabling azenosertib data readout from DENALI Part 2Planned workforce ...