Patients are significantly more likely to experience treatment-related cardiac events with osimertinib than with other EGFR TKIs, data suggest.

The purpose of this study was to investigate whether circulating pyruvate kinase M2 (PK‐M2) levels are elevated in the peripheral blood and to assess their association with diagnosis and prognosis in ...

AF6 denotes afadin, GAP GTPase-activating protein, GEF guanine exchange factor, MEK mitogen-activated protein kinase kinase ... ERK-dependent phosphoprotein network by measuring changes in ...

Get Instant Summarized Text (Gist) A three-drug cocktail has been identified to enhance CAR-T cell therapy by preserving T-memory stem cells (T SCM), crucial for long-term persistence.The cocktail ...

Discover the key types of network traffic and their role in optimizing performance plus real-world examples to see how they impact data flow. Identifying network traffic types is vital because it ...

Everything you stream and share is broken into network packets. Learn how this enables the seamless flow of data that powers the internet. Network packets are small units of data that are sent ...

Trametinib, a mitogen-activated protein kinase (MEK) inhibitor, reduces mortality and morbidity in children with severe hypertrophic cardiomyopathy (HCM) caused by pathogenic variants in the RAS ...

Kinases have a pivotal role in phosphorylation and kinase dysregulation has been implicated in the occurrence and progression of various diseases. By mid-2024 the Food and Drug Administration had ...

The Find My Device network was full of promise, but Android’s alternative to the tech behind Apple’s AirTag launched to a rough start in 2024. Over time, though, it seems to finally be getting ...

In control ECs, F-actin filaments were organized in a cortical network (Figure I-C). Two minutes after activation with LPA ... To investigate whether ongoing MLC kinase activity was also required for ...