We discuss the challenges such as immunosuppressive microenvironment, tumor heterogeneity, and physical barriers that limit CAR-T efficacy. Emerging strategies, such as logic-gated and dual-targeting ...

When a child develops a brain tumor, early diagnosis is essential. Alan Cohen, M.D., director of pediatric neurosurgery at Johns Hopkins Children’s Center, shares the most common signs and symptoms ...

it didn’t occur to me that it might be a highly effective toilet bowl cleaner until I was faced with the persistent toilet stain situation. (I hate to even type those words.) I assumed it was ...

We further found that neurons with accumulation of phospho-tau immunostaining contained rG4s, that rG4 structure can drive tau aggregation, and that rG4 staining density depended on APOE genotype in ...

Effect size analysis indicated that 5FU had the most substantial impact, followed by the combination treatment, while DOX showed a moderate effect in reducing tumor growth (Supplementary Table S1).