Research indicates mulberry extract's efficacy in addressing obesity-related male infertility, enhancing reproductive outcomes through bioactive compounds.

Leptin is an essential hormone that is closely linked to the regulation of hunger and metabolic processes. It works by signaling the brain when the body is satiated with nutrients, which aids in ...

Cavendish Laboratory, Department of Physics, University of Cambridge, J. J. Thomson Avenue, Cambridge CB3 0HE, U.K. ISIS Neutron and Muon Source, STFC Rutherford Appleton Laboratory, Harwell Science ...

Amylin has important physiological effects including reducing appetite, increasing satiety, leptin sensitivity and energy expenditure ... as both approaches have demonstrated potential as obesity and ...

Structure Therapeutics is positioning itself as a leader in the small molecule obesity treatment ... of amylin agonists to potentially increase leptin sensitivity and energy expenditure, along ...

Amylin has important physiological effects including reducing appetite, increasing satiety, leptin sensitivity ... management treatment. Structure’s lead amylin-based molecule, ACCG-2671 ...

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Mice lacking Slc39a5 function are protected against hepatic steatosis and hyperglycemia resulting from diet-induced obesity or leptin-receptor deficiency and display reduced hepatic ... fluorescence ...

Shanghai Engineering Research Center of Molecular Therapeutics & New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China ...

Furthermore, understanding the mechanism of action in metabolic disorders can allow us to harness their inflammatory potential. Leptin affects a wide range of metabolic processes as well as being a ...

The structure elucidates the chemical basis of plant polyketide biosynthesis and provides a framework for engineering CHS-like enzymes to produce new products. Despite significant advances in the ...

Molecular Cancer Therapeutics publishes articles on the discovery and preclinical development of novel therapeutic agents for oncology, preclinical studies of approved therapeutics, mechanisms of drug ...