a research group developed a highly sensitive proteomics method called peptide-centric local stability assay (PELSA), which enables the simultaneous identification of ligand-binding proteins and ...

Ligand-binding assays are used for both characterization and quantitation of biotherapeutic drugs, however, current analytical approaches may no longer be sufficient for analyzing emerging drug ...

High-resolution time-of-flight mass spectrometry (TOF-MS) can be used for this analysis offering several advantages over ligand-binding assays or fluorescence-based liquid chromatography. Notably, TOF ...