Interactions at a ligand binding level had been proposed and were strengthened by mounting pharmacological evidence. Binding assays were critical in assessing the hypothesis that opioid receptors ...

a research group developed a highly sensitive proteomics method called peptide-centric local stability assay (PELSA), which enables the simultaneous identification of ligand-binding proteins and ...

Researchers now offer a simplified method they call ProteinReDiff that uses artificial intelligence to speed the redesign of ligand-binding proteins. In biology, the binding of cellular proteins ...

Ligand-binding assays are used for both characterization and quantitation of biotherapeutic drugs, however, current analytical approaches may no longer be sufficient for analyzing emerging drug ...