DNA 聚合酶在 DNA 复制过程中发挥着关键作用，其主要形成磷酸二酯键，以确保遗传信息的准确传递。同时，这一过程还涉及到多种相关的化学反应和酶的协同作用。 1. 磷酸二酯键的形成机制：DNA 聚合酶通过催化脱氧核苷酸之间的反应，将一个脱氧核苷酸的 5'磷酸基团与另一个脱氧核苷酸的 3'羟基相连，从而形成磷酸二酯键。这是 DNA 链延长的基础。 2. 对 ...

How can DNA from a cheek swab determine if someone is closely related to you? When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works. DNA tests can ...

Thus, its activation represents a therapeutic strategy to combat obesity. Here, we demonstrate that levels of F-box and WD repeat domain-containing 7 (FBXW7), an E3 ubiquitin protein ligase, ...

They applied the new method to more than 1,500 European genomes (a person's complete set of DNA) from people who lived primarily during the first millennium AD (year 1 to 1000), encompassing the ...

Ancient DNA unlocks new understanding of migrations in the first millennium AD. ScienceDaily . Retrieved January 25, 2025 from www.sciencedaily.com / releases / 2025 / 01 / 250101132012.htm ...

Department of Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China Institute of Integrated Bioinfomedicine and Translational Science (IBTS), ...

Here, we identified RNF146 as a ubiquitin ligase (E3) of TEADs, which negatively regulates their stability in cells ... Total RNA was extracted using the Qiagen RNAeasy kit with the on-column genomic ...

Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, Institute of Developmental Biology and Regenerative Medicine, College of Chemistry and ...

DNA replication is the biological process by which an exact copy of a deoxyribonucleic acid (DNA) molecule is created and it is the basis for biological inheritance. Each of the two strands of the ...

If stored as DNA, every film ever made could be stored in a space smaller than a sugar cube Scientists say they have made a major step forward in efforts to store information as molecules of DNA ...