While resident adipose tissue macrophages display an anti-inflammatory phenotype and promote the development ... As the NADPH oxidase catalytic subunit, NOX2 has been demonstrated to be involved in ...

The visceral adipose tissue (VAT) is a site that becomes dysfunctional during obesity and aging ... worsened metabolic parameters through the activation of VAT macrophages and plasmacytoid dendritic ...

Researchers found that high fructose intake, especially from processed foods, is linked to metabolic dysfunction-associated ...

They used multi-tissue network analysis to study the effects of the JNK inhibitor JNK-IN-5A on metabolic dysfunction associated with excessive sucrose consumption. Their results show that JNK ...

Objective Obesity is a risk factor for non-alcoholic steatohepatitis (NASH). This risk has been attributed to visceral adipose tissue (vAT) expansion associated with increased proinflammatory ...

Coexpression analysis and genome-scale metabolic modeling reveal that sucrose overconsumption primarily induces transcriptional dysfunction related to fatty acid and oxidative metabolism in the liver ...

Recognizing obesity as a chronic disease can improve treatment, address complications, and reshape healthcare strategies for ...

When metabolic endotoxemia was induced for 4 weeks in mice through continuous subcutaneous infusion of LPS, fasted glycemia and insulinemia and whole-body, liver, and adipose tissue weight gain ...

Metabolic dysfunction-associated steatotic liver disease, or MASLD, is an umbrella term describing conditions related to a ...

There's a growing body of evidence that gold nanoparticles can offer significant, targeted weight loss that focuses on fat ...