What is the impact of losartan therapy (focusing on the drug's blood pressure-lowering effect only) on 10-year stroke risk, as calculated from the Framingham Stroke Risk Score, in these patients?

During both 18-week periods, patients received each of the following for 6 weeks, in random order: placebo; losartan (100 mg/day); and losartan (100 mg/day) plus hydrochlorothiazide (25 mg/day).

Lastly, Lacourciere and Asmar [7] compared the effects of candesartan cilexetil 8 mg force-titrated to 16 mg (n=116) and losartan 50 mg force-titrated to 100 mg (n=115) once daily, as assessed by ...