Researchers explore the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during ...

The primary induction sites for intestinal IgA are the gut-associated lymphoid tissues (GALT), such as Peyer's patches (PPs) and isolated lymphoid follicles (ILFs). The commensal microbiota is known ...

Scientists used high-resolution 3D X-ray imaging to uncover major structural and immune changes in the gut of Alzheimer's ...

Depicted is the follicle-associated epithelium (FAE) and the Peyer’s patches (PP) germinal centers and the isolated lymphoid follicles (ILF), where these cell interactions occur and are considered to ...

Secondary lymphoid organs (SLOs), such as the lymph ... These cells shuttle from the marginal zone to the follicle and can therefore transport antigen independently of the BCR, through its binding ...

Table 2. Distinction between atypical lymphoid proliferations rich in Reed–Sternberg-like cells (reactive immunoblasts) and classic Hodgkin lymphomas. Aspects Atypical lymphoid proliferations ...

In their absence due to genetic deletion of RORγt, lymph nodes and Peyer's patches do not develop,99 and they are also required for the generation of isolated lymphoid follicles in the mucosa which ...

1 LIIPAT, Institute of Pathology and Centre for Immune Regulation, University of Oslo and Oslo University Hospital, Oslo, Norway 2 Department of Pediatrics, Oslo University Hospital, University of ...

Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the induction of high-affinity antibodies derived from GCs and produced by ...