A variety of non-malignant stromal cells present at the complex tumor microenvironment are active players in cancer progression (1). Specifically in solid tumors, tumor associated macrophages (TAMs) ...

Researchers explore the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

Homeostasis is the result of variables being regulated such that the internal environment remains stable and fairly constant even though the external environment varies. For example, in humans ...

Chemotherapy for breast cancer may be more effective during specific stages of the menstrual cycle, according to data from ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...