Other macrophage models have been developed but lack certain features unique to alveolar macrophages. The AML model solves ...

The studies demonstrated the feasibility of the approach using cell-mediated catalase delivery for neuroprotection of dopaminergic neurons in a mouse model of Parkinson's disease.

[3] Compared with intact caps, the ruptured ones usually are thinner and contain less collagen, have fewer smooth muscle cells and are heavily infiltrated by macrophage foam cells. [3,13] These ...

Macrophages are immune cells that reside in ... These changes, in the fibrotic injury model, caused distinct pathways to be activated that led the cells toward a less effective repair, as a ...

According to the Centers for Disease Control and Prevention, more than two in five American adults have obesity, a common and costly chronic disease. Linked to chronic conditions like type 2 diabetes ...

Atherosclerosis risk is elevated in diabetic patients, but the underlying mechanism such as the involvement of macrophages remains unclear. Here, we investigated the underlying mechanism related to ...