A computer model of the cellular environment inside the knee developed by UT Southwestern Medical Center researchers sheds ...

Hamilton et al. demonstrated a decrease in proportion of iNOS and reduction of pro-inflammatory macrophages after MSCs injection in a murine OA model (78). It was reported that MSCs decreased synovial ...

The studies demonstrated the feasibility of the approach using cell-mediated catalase delivery for neuroprotection of dopaminergic neurons in a mouse model of Parkinson's disease.

Nanoformulated catalase (nanozyme) obtained by coupling the enzyme to a synthetic polyelectrolyte of opposite charge was loaded into bone marrow macrophages ... in a mouse model of Parkinson's ...

Find out why stress can worsen allergy symptoms. Learn about the cellular chain reaction that occurs in the body and how it ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical studies have implicated macrophage-mediated immune tolerance. Hence, pathways ...

Atherosclerosis risk is elevated in diabetic patients, but the underlying mechanism such as the involvement of macrophages remains unclear. Here, we investigated the underlying mechanism related to ...

NuFund Venture Group announces investment in Resolute Science, a preclinical-stage biotechnology company developing a pan-cancer platform targeting tumor-associated macrophages to deliver cytotoxic ...

The underlying regulatory mechanisms of metabolic switching are assessed by both in vitro and in vivo studies. Conclusions Selectively modulating the ‘context’ of glycolytic macrophages in HCC tumours ...