Breakthrough NUS discovery sheds light on cellular recycling mechanism and potential for treating rare diseases Singapore ...

An increase in high-fat, high-fructose foods in people's diets has contributed to a dramatic increase in type 2 diabetes.

Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS ...

These cells play a critical role in the ... compared to those from younger individuals. These aged macrophages exhibited ...

Macrophages mediate a limited-specificity ... constituting an inflammatory response, the binding and phagocytosis of apoptotic cells results in a non- (or anti-) inflammatory response.

This adds to the growing body of work, from mouse and fly models, implicating lipid metabolism in neurodegeneration, particularly AD,” Amita Sehgal, Perelman School of Medici ...

Understanding why newborns, but not adults, can regenerate the heart could lead to treatments that "reprogram" adult macrophages.

Her training and primary interest is in cell and ... upregulated phagocytosis, and the ability to participate in the activation of adaptive immune responses. During a typical immune response, the ...

Carisma Therapeutics is developing a unique, differentiated immuno-oncology (IO) treatment for solid tumors based on chimeric antigen receptor macrophages (CAR-M). Current IO treatments have ...