Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

Mutations in NPC1 cause Niemann-Pick Type C. Mice lacking NPC1 only in microglia have rampant neuroinflammation and impaired ...

Using lineage tracing, we find that tissue-resident red pulp macrophages (RPM), initially depleted by BCG exposure ... MARS-seq pipeline 57 was used for demultiplexing, alignment to the genome (mm9), ...

Some genes are beneficial and enhance longevity. For example, the gene that helps a person metabolize cholesterol would reduce a person's risk of heart disease. Some gene mutations are inherited.

Immunohistochemical localization of oxPL contrast agent within atherosclerotic plaque confirmed selective accumulation in macrophages. Phagocytosis of oxPL in human macrophages involves α v β 3 ...

In particular, the adipose tissue macrophages (ATMs) are important in the pathogenesis of obesity ... There are several markers that confirm the exosome’s structural organization, including CD63, CD81 ...

Human monocyte-derived macrophages (hMDM) were differentiated from CD14 + monocytes of healthy controls, patients with SSc, RA, PsA, and axSpA. In some experiments hMDMs pretreated with 0.1 μM ...

These could be signs that you have an inherited intolerance to alcohol — and a mutated gene could be the culprit, according to Cleveland Clinic. This gene mutation hampers the body’s ability ...

A mutant gene is coming to steal Linde Jacobs’s mind. Can she find a way to stop it? A mutant gene is coming to steal Linde Jacobs’s mind. Can she find a way to stop it? Credit...Mike Kai Chen ...