Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

Mutations in NPC1 cause Niemann-Pick Type C. Mice lacking NPC1 only in microglia have rampant neuroinflammation and impaired ...

Immunohistochemical localization of oxPL contrast agent within atherosclerotic plaque confirmed selective accumulation in macrophages. Phagocytosis of oxPL in human macrophages involves α v β 3 ...

Human monocyte-derived macrophages (hMDM) were differentiated from CD14 + monocytes of healthy controls, patients with SSc, RA, PsA, and axSpA. In some experiments hMDMs pretreated with 0.1 μM ...

These could be signs that you have an inherited intolerance to alcohol — and a mutated gene could be the culprit, according to Cleveland Clinic. This gene mutation hampers the body’s ability ...