Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non ...
The FDA has approved Amgen and Allergan’s biosimilar of Roche’s Herceptin, just in time for the breast cancer blockbuster’s patent expiry. Herceptin’s main US patent expires this month ...
Despite the impact of the pandemic on cancer care, Perjeta grew 17% to CHF 2.9 billion ($3.2 billion) in the first nine months of 2020, now just fractionally behind Herceptin which declined 31% to ...
This article will review the mechanisms of activation of alternative, classical, and lectin pathways, the formation of C3 and C5 convertases, the action of anaphylatoxins, and the ...
ORF3a, an accessory protein of SARS-CoV-2, mediates the transmembrane transport of water, leading to lysosome swelling. This function could, in principle, result in lysosome inactivation, a ...
The most commonly mutated ALS-linked genes are reviewed with an emphasis on disease-causing mechanisms. The cellular processes involved in ALS pathogenesis are discussed, with evidence implicating ...
As an additional means of meeting these targets, the Kyoto Protocol introduced three market-based mechanisms, thereby creating what is now known as the carbon market. Stimulate sustainable development ...
The scarcity has left vulnerable populations at significant risk, with public health experts warning that prolonged stockouts ...
We see the seven stones of the Molecular Systems Biology cover as a visual allegory for Aristotle's visionary thought: The whole is greater than the sum of its parts.
PM Modi must admit 'Make in India' failed, says Rahul Gandhi; BJP hits back NEW DELHI: Congress MP Rahul Gandhi Wednesday alleged that Prime Minister Narendra Modi did not mention the 'Make in ...
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