Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain.

A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the ...

1Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida. 2Cancer Biology PhD Program, University of South Florida, Tampa, Florida.

When evaluating the correlations between the rates of suspected malignant neoplasms of the skin and the other covariates, the proportion of consultations for males, brown-skinned individuals, people ...

This study shows that depressive symptoms at baseline were associated with poor survival in patients with newly diagnosed metastatic EGC. Therefore ... Clinical characteristics included group (ESC ...

It was registered at ClinicalTrials.gov (identifier: NCT04120298). After providing written informed consent, patients with mBC with a life expectancy of ≥6 months and without unstable bone metastases ...

There is a simple discount patient access scheme for tebentafusp. NHS organisations can get details on the Commercial Access and Pricing (CAP) Portal. Non-NHS organisations can contact ...

Results: Seventeen patients were enrolled, of which 16 patients had papillary and 1 had collecting duct histology ... an active regimen in patients with metastatic papillary RCC.

The stage of a melanoma skin cancer tells you how thick it is and if it has spread. It helps your doctor decide the best treatment for you. TNM stands for Tumour, Node, Metastasis. TNM staging for ...

4Vagelos College of Physicians and Surgeons, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York. 5Department of Pathology and Cell Biology, Columbia University Irving ...