Disparate pathogenic mechanisms complicate precision-medicine efforts to treat diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis. Though potentially curable with frontline ...

A novel mechanism that enables cells to maintain energy production even when their main power supply drops/fails has been ...

The FDA has extended the review period for the New Drug Application for elamipretide for the treatment of Barth syndrome.

Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen ...

Aligning therapies with the biologic clock may improve efficacy, as macrophage activity peaks early in the morning, worsening inflammatory disease symptoms.

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death.

Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen species (ROS) management and Ca2+ signaling.

In biology textbooks, the endoplasmic reticulum is often portrayed as a distinct, compact organelle near the nucleus, and is commonly known to be responsible for protein trafficking and secretion. In ...

A study published by the Journal of Traditional and Complementary Medicine and e-published by the U.S. National Library of Medicine highlights cannabidiol’s (CBD) potential as a therapeutic option for ...

mitochondrial membrane potential loss, and permeability transition pore activation, which can culminate in cell death. A review by a team of researchers at the Chinese Academy of Science ...

That’s why it’s counterintuitive to think low oxygen could be a therapy for chronic conditions ranging from mitochondrial diseases and autoimmune disorders to Parkinson’s and even aging.