proposing that mitochondria are the source of the free radicals. As Harman’s free-radical theory of aging took hold, it fueled research into cancer, Alzheimer’s and many other diseases.

Vijg describes this genome and discusses the significance of DNA damage to mitochondria, which may be an important signaling factor in the aging process. A leading theory of aging, which he ...

(Mitochondrial DNA, in contrast ... Key Concepts in the Genetic Theory of Aging The key concepts in genetics and aging include several important concepts and ideas ranging from telomere shortening ...

(Mitochondrial DNA, in contrast, carries much less genetic information and is ... These include cystic fibrosis and sickle cell anemia, to name a couple. Key Concepts in the Genetic Theory of Aging ...

The PAMRP theory combines these two perspectives ... species and the link between metabolism and aging-related factors like entropy and mitochondrial function. Caloric restriction, which is ...

New research identifies E-TCmito as a key link between neuronal activity and mitochondrial function, highlighting its potential to address cognitive decline in aging and diseases like Alzheimer’s. New ...

Scientists have long debated the root causes of Alzheimer’s, with two main theories emerging. The first centers on the ...