Objectives Bone destruction in rheumatoid arthritis is mediated by osteoclasts (OC), which are derived from precursor cells of the myeloid lineage. The role of the two monocyte subsets, classical ...

Monocytopenia describes a low number of monocytes, a type of white blood cell. Monocytes are made in the bone marrow and account for 2% to 6% of white blood cells at any given time. They work ...

JAKs are important kinases in lymphocyte differentiation; however, their function in dendritic cells (DCs) is unknown. In this study, the function of JAKs in DCs was investigated with tofacitinib.

The presence of microplastics in our food and soil has become a global-level crisis. A young girl named Anushka Sable has found that they can cause tumor in our bodies.

Dec. 18, 2024 — Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build ...

Jan. 3, 2025 — Biologists have shown that the surfaces of plant leaves are coated with a diverse array of RNA molecules. The finding suggests that the RNA present ...

Their work builds on previous findings linking chronic inflammation in people with HIV to cerebrovascular disease and ...

Supernatants obtained from resting, PMA/Iono activated, or co-culture activated PB-NK and PB-CAR-NK cells were incubated with primary monocytes. BMCA was assessed by measuring IL-6 and IL-1β secreted ...

This study investigates the impact of myenteric neuron-macrophage interactions on postoperative trauma and subsequent ...

Loss of the Y chromosome (LOY) in men, a dynamic mutation linked to aging, impairs immune function and increases risks of ...