Starting from the hypothesis that immune cells promptly respond to harmful stimuli, we used peripheral blood monocytes in order to characterise a distinct gene expression profile and to evaluate its ...
The aim of this study was to test if adalimumab treatment could affect the influx of monocytes into the synovium. Methods A novel technique was used to analyse the migration of labelled autologous ...
This study involved 5260 participants aged >18 years old from the Dalian health management cohort in 2014 to 2022. The subjects were stratified into 4 groups based on the quartile of the MHR at ...
Bone remodelling results from the balance between two tightly regulated phenomena: osteoclastogenesis and osteogenesis. The osteoclast is a bone-resorbing cell with an origin in the ...
Monocytopenia describes a low number of monocytes, a type of white blood cell. Monocytes are made in the bone marrow and account for 2% to 6% of white blood cells at any given time. They work ...
Cx-43, Connexin 43; EMT, Epithelial to Mesenchymal Transition; ERK, Extracellular-signal Regulated Kinase; FVII, Factor VII; FX, Factor X; FXa, activated FX; HIF1-α, Hypoxia-Inducible Factor-1; LC3, ...
Early inhibition of STAT1 activation, using specific JAK-STAT inhibitors, reduces both RPM loss and recruitment of trained monocytes. Our study suggests a temporal window soon after BCG vaccination, ...
Early inhibition of STAT1 activation, using specific JAK-STAT inhibitors, reduces both RPM loss and recruitment of trained monocytes. Our study suggests a temporal window soon after BCG vaccination, ...
LCs were even present in the nose and ears of aged mice. Depending on the location, the stiffness and pliability of cartilage varies. The team wanted to understand how the lipid vacuoles inside LCs ...