Arthritis & Rheumatism. 2006;54(12):3859-3867. Degenerative disc disease is one of today's most common and costly medical conditions. Marked by the gradual erosion of cartilage between the ...

However, it is unknown whether IVD tissue contains functional circadian clocks and if so, how their dysregulation is implicated in IVD degeneration. Results Here we show the existence of the circadian ...

27, 2025 — Heart disease remains the leading cause of death ... with few effective treatments. A team has now identified an enzyme, alpha-kinase 2 (ALPK2), that is specifically ...

Two new medications, called lecanemab and donanemab, have shown success in clinical trials in slowing down Alzheimer’s disease. These are known as disease-modifying treatments and have been licensed ...

The high-quality studies showed that thermal RFA of the DRG is not effective in the treatment of chronic lumbar radicular pain. The trial results provided inconclusive evidence of the efficacy of ...

Jan. 15, 2025 — Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research points to a ...

“There’s been a lot of progress in rare disease diagnosis in the last decades, as well as an increasing number of treatments. When the FDA Orphan Drug pathway was put in place in ...

Finally, the fused multi-scale features are sent to the classifier to discriminate disease-related OCT images. The proposed model has the potential to accurately detect retinal diseases and can be ...

because a significant proportion of these patients will have HF caused by hypertension or valvular heart disease. With the inclusion of the pediatric population and the worldwide spectrum of causes of ...

Medications are the mainstay of treatment for multiple sclerosis (MS). Many of them are used to block the immune system's attack on the nerves and slow or prevent progression and relapses (flare-ups) ...