In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.

Icovamenib is under clinical development by Biomea Fusion and currently in Phase II for Type 1 Diabetes (Juvenile Diabetes).

Share on Pinterest Do all our cells have a type of memory, and if so, how might this influence health? We investigate. Design by MNT; Photography by Grant Faint/Getty Images & Ed Reschke/Getty Images.

Hence, generation of lineage-specific knock-out mouse models is essential to avoid these systemic effects and unequivocally define the role of JAM-A in the regulation of myeloid cell recruitment and ...

Myeloproliferative neoplasms are blood cancers that affect myeloid stem cells. Treatment can involve targeted medications or careful monitoring. Myeloproliferative disorders are a group of cancers ...

Thus, in this review, we summarize our current understanding of the interaction between nociceptors and, specifically, the myeloid cells of the innate immune system, while pointing out some of the ...

A cell lineage is the developmental history of a differentiated cell as traced back to the cell from which it arises. The cells of some organisms, such as C. elegans, have invariant lineages ...

Smooth muscle cells (SMCs) of the proximal thoracic aorta are derived from second heart field (SHF) and cardiac neural crest (CNC) lineages. Recent studies, both in vitro and in vivo, have implied ...

From the Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany (D.W.) Faculty of Medicine, University of Freiburg, Germany (D.W.) K. Ley has received research funding for ...

Stocks: Real-time U.S. stock quotes reflect trades reported through Nasdaq only; comprehensive quotes and volume reflect trading in all markets and are delayed at least 15 minutes. International ...

The popular custom ROM called Lineage OS just got updated to Android 15 officially with new build version 22.1 in stable channel. This brings the Android 15 to even more smartphones from various OEMs ...