Sphere of Influence. In iAssembloids, microglia (red) form projections (white arrows), while astrocytes (green) assume star shapes typically found in the brain. [Courtesy of Kampmann et al., 2025.] ...
Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.
For over a decade, smaller clinical trials have explored the safety and feasibility of these particular stem cell approaches and found them beneficial for people with MS. Neural stem cells are ...
Their findings indicate these cells play a key role in initiating NPC pathology ... 18F-GE-180 picked up more translocator protein 18 kDa (TSPO), a marker of microglial activation (image at right), ...
Since all cells in the body share the same complete genome, including the CREB gene, and this protein is also present in tissues with different functions, Kukushkin and his team decided to investigate ...
After years of controversy, stem cells are on the cusp of cures for conditions like epilepsy and type 1 diabetes. California Institute for Regenerative Medicine, Neurona Therapeutics, Vertex ...
Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and ...
This included the identification of specific pro-inflammatory microglial clusters and age-depleted neural stem cell populations. Particular attention was given to sparsely distributed populations ...
Detailed mapping of 1.2 million brain cells has revealed that not all cell types age in the same way and that some – found in a specific ‘hot spot’ – are more sensitive to the aging process.