Reversing opioid overdoses in rats using a drug that does not enter the brain prevents the sudden and severe withdrawal symptoms associated with therapeutics that target the central nervous system.
The global burden of anxiety- and depression-related disorders is on the rise. While multiple drugs have been developed to treat these conditions, current medications have several limitations, ...
School of Pharmacy, The University of Queensland, Brisbane 4102, Australia Inflammatory Bowel Diseases Group, Mater Research Institute─UQ at Translational Research Institute, The University of ...
The structure of the EphA4 receptor SAM domain reveals a novel mechanism through which modular domains control protein–protein interactions. Since SAM domains are found in cell surface receptors ...