in an orthotopic mouse model. One week of treatment of tumour-bearing immunocompromised RIP1-Tag2 mice with the anti-VEGFR2 antibody DC101 resulted in significantly more invasive tumours ...
To address this, we have established an orthotopic mouse model for study that recapitulates the aggressive clinical progression of radiorecurrent prostate cancer. Radiorecurrent DU145 cells which ...
Methods ICB-resistant orthotopic-grafted murine models were established via a serial selection of HCC cells in ICB-treated mice. A genetically engineered mouse model was established via hydrodynamic ...
Design Functional significance of MDSCs was evaluated by flow cytometry using two orthotopic HCC models in fibrotic liver setting via carbon ... resulting in tumour eradication and prolonged survival ...