Clinicians discuss the rapidly evolving therapies, technology, and surgical approaches for early-stage NSCLC and take a fresh look at the future of care. Teamwork: A Multidisciplinary Approach to ...

Background: The Beclin-1/Bcl-2 complex plays a pivotal role in regulating both autophagy and apoptosis in osteoblasts affected by osteoporosis. This study first investigates whether the Bushen Jianpi ...

We are interested in molecular mechanisms underlying neural development, neuro-degeneration, and bone homeostasis. Although neural development, neurodegeneration, and bone homeostasis are three ...

Pathology is the precise study of the causes and consequences of a disease. The two major components of pathology are anatomical studies of structure and function at levels ranging from the whole ...

with greater amounts of viral proteins co-localized with tangles of phosphorylated tau -- one of the hallmarks of Alzheimer's disease pathology -- in brain regions especially vulnerable to ...

Correspondence to Dr Russell James Everett, BHF/Centre for Cardiovascular Science, University of Edinburgh, Edinburgh EH16 4SB, UK; russell.everett{at}ed.ac.uk To review the pathophysiology of ...

Marfan syndrome (MFS) is an inherited disorder that affects the connective tissues and mainly presents in the bones, eyes, and cardiovascular system, etc. Aortic pathology is the leading cause of ...

The purpose of this review is to describe the available evidence for osteoporosis treatments in young and premenopausal women. A review of articles evaluating the treatment or prevention of ...

This valuable study presents findings on the mode of action of MOTS-c (mitochondrial open reading frame from the twelve S rRNA type-c), and its impact on monocyte-derived macrophages. The authors ...

Statins have been shown to interfere with osteoclast function by a pathway independent of their anti-inflammatory effects, with suppression of bone resorption demonstrated in vitro; they have also ...

This heterogeneity may account for the failure to develop therapeutics that block calcification and will prove informative for the future development of targeted treatments for this detrimental ...