The Royal Osteoporosis Society explain what osteopenia and osteoporosis mean and how diet, lifestyle and genetic factors can affect bone density.

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements.

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements.

Through our multidisciplinary effort, we aimed to develop advanced bone repair materials capable of mimicking the stability of healthy trabecular bone while promoting bone healing by reducing the ...

A team of researchers has developed a new biomaterial with high potential in in the treatment of bone lesions or minimal residual disease in multiple myeloma patients. The findings showcase a ...

In diabetic patients, high blood glucose decreases osteoblast and osteoclast activity, and Wittrant ... Cluster 3 is characterized by the core terms “osteoporosis”, “bone turnover”, “male” and “female ...

Skeletal remodeling is mediated by the integrated and tightly coupled actions of mechano-sensing osteocytes, bone-resorbing osteoclasts and bone-forming osteoblasts (Figure 1).

Osteoporosis ... with new tissue created by cells called osteoblasts; bone begins to weaken when bone resorption exceeds bone formation. Circulating osteoclast precursor cells exacerbate bone ...

The current available pharmacological treatments for osteoporosis are anti-resorptive (inhibiting the osteoclasts), bone forming (stimulating the osteoblasts) or dual acting (simultaneously ...

osteoclasts and osteoblasts. Current therapies for the prevention and treatment of osteoporosis are limited by efficacy and patient compliance. RANKL/osteoprotegerin/RANK signaling regulates bone ...