HIV-1 感染后，在记忆 CD4 T 细胞中形成的潜伏库是实现功能性治愈的主要障碍。尽管抗逆转录病毒疗法（ART）能有效抑制病毒复制，使患者血浆病毒载量检测不到，阻止疾病进展，但一旦停药，病毒就会从潜伏库中重新激活，导致病毒血症复发。“休克 - 杀伤” 策略是目前极具潜力的清除潜伏库的方法，即利用潜伏逆转剂（LRAs）激活潜伏感染细胞中的 HIV-1，再通过细胞毒性淋巴细胞（如 HIV-1 ...

To evaluate the impact of potential NFAT inhibitors on the activation of NFAT, 4 × 10⁵ cells suspended in 180 μL of medium were stimulated with PMA (50 ng/mL) and ionomycin (3 μg/mL) to induce NFAT ...

“If you add up this one, including PMA (Philippine Military Academy), PNPA (PNP Academy) and other offices with primary responsibility for education in their particular areas, that could add up ...

MANILA – Malacañang on Tuesday said there is nothing wrong with the Philippine Military Academy (PMA) and the Philippine National Police Academy’s (PNPA) inclusion in the 2025 funding for the ...