This interesting manuscript describes a study investigating the role of MC4R signalling on kisspeptin neurons. The initial question is a good one. Infertility associated with MC4 mutations in humans ...

The study presents compelling evidence that the melanocortin system originating in the arcuate nucleus of the hypothalamus plays a crucial role in puberty onset, representing a significant advance in ...

Leptin, in contrast, inhibits these neurons and stimulates POMC neurons, which make you feel full. But how temperature influences this intricate system is "still an open area of investigation ...

Horvath and his team discovered that THC flipped a switch in the mouse’s hypothalamus, with a cluster of neurons, called the POMC neurons, telling the hypothalamus you’re hungry rather than ...

In addition, alcohol increases ghrelin levels to promote appetite. This combined effect drives overeating of calorie dense foods. “Alcohol also suppresses pro-opiomelanocortin (POMC) neurons, a type ...

and anorexigenic pro-opiomelanocortin (POMC)/cocaine- and amphetamine-related transcript (CART) neurons that modulate appetite control. There are projections from the ARC to other hypothalamic ...

Mirror neurons received significant media attention in the 2000s and were painted by some scientists as the key to many of our advanced social abilities. However, many of the more significant ...

Various external factors modulate the metabolic efficiency of mitochondria. This review focuses on the impact of the growth factor neuregulin and its ErbB receptors on mitochondria and their ...

Jan. 22, 2025 — Thermal sensations are consciously differentiated as hot or cold by the brain; however, the neural mechanism that enables this differentiation is not well understood. To address ...

Intracellular lipid transport can occur by flip‐flop from one side of a bilayer to the other, by vesicular trafficking, by lipid transfer proteins, or by diffusion within a bilayer 34. MAMs are hubs ...