A dysfunctional signaling pathway in the hippocampus has been linked to chronic pain-related memory impairment in mice.

A network of nerves similar to wires runs all through the human body, from the tips of your fingers and toes, through your back inside the spinal cord and up to your brain. Specialized pain receptors ...

Again, the effect of ovarian steroids on pain responsiveness in rats can be seen in humans, where women approaching the time of ovulation produce more opiate receptors in key parts of the brain ...

Unrelieved pain has major negative effects on the lives of millions of people worldwide, and is associated with huge societal costs. Breakthroughs in pain therapy have been rare in the past 50 ...

A growing body of research suggests crabs, lobsters and other animals caught for seafood can feel pain. Scientists are pushing for legal protections to ensure they are treated humanely.

Capsaicin binds to pain receptors on our nerves called TRPV1. Normally, it reacts to heat by sending warning signals to the brain. Capsaicin causes TRPV1 to send those same signals. So ...

If an artificial painkiller such as morphine is given, it occupies more of the pain receptors in the brain; however, less natural painkiller is released. Then, when the artificial source is taken ...

It binds to the same receptors in the brain as marijuana and produces the same warm, fuzzy feeling. And it’s not just chemicals that determine how we feel pain. More from Science Similar areas ...

Our acute pain system sends signals from nerve receptors in an affected area (a bad tooth or burned hand) to the brain which ...

Reversing opioid overdoses in rats using a drug that does not enter the brain prevents the sudden and severe withdrawal symptoms associated with therapeutics that target the central nervous system.