Pancreas cells may produce a protein that can protect the brain from Alzheimer's disease. In individuals with Alzheimer's disease, a peptide known as amyloid-β accumulates and forms tangled plaques.
This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...
Results of the study at four weeks after cell transplantation demonstrate the survival and function of pancreatic beta cells as measured by the presence of circulating C-peptide, a biomarker ...
Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.
More information: Esra Karakose et al, Cycling alpha cells in regenerative drug-treated human pancreatic islets may serve as key beta cell progenitors, Cell Reports Medicine (2024). DOI: 10.1016/j ...