Notably, FIP excludes peri-pancreatic fat, also called extra-lobular fat (2, 3). The lack of clear differentiation between triglyceride accumulation in acinar cells, beta cells, or intra-pancreatic ...

Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.

Bone-marrow-derived multipotent progenitor stromal cells — or mesenchymal stem cells (MSCs) — are the common predecessors of cells of the mesenchymal lineage, such as bone, cartilage and fat ...

Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells do not express ...

Jan. 30, 2025 — A research group has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells. This groundbreaking research opens doors ...

Pancreatic cancer is genetically diverse. Patient-derived xenografts are considered the most reliable avatar of individual patient tumour. Pancreatic cancer cell lines are believed to poorly represent ...

Objective Pancreatic ductal adenocarcinoma (PDAC ... and converted CAFs into myoCAFs, which hijacked low metastatic cancer cells for metastasis. The interleukin (IL)-33–ST2–TAMs axis was the primary ...

Multiple diagnostic criteria have been proposed. For example, the Japanese Pancreas Society (2002 and 2006) and Histology, Imaging, Serology, Other Organ Involvement and Response to therapy (HISORt).

Learn about cystic fibrosis, a genetic disorder that affects the lungs, pancreas, and other organs, and how to treat and live with this ... When the protein is not working correctly, it’s unable to ...

This had never happened before. There is a remarkable story behind these cells; it's more than half a century old, but still relevant and current. Dr Maninder Ahluwalia, senior lecturer in ...

Supplements for diabetes such as chromium, cinnamon, and berberine may help control blood sugar. Research also suggests that omega-3 fatty acids and magnesium may offer a protective benefit, lowering ...