This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Diabetes affects an estimated 415 million people worldwide, with type 2 diabetes (T2D) accounting for about 90% of these ...

Pancreas cells may produce a protein that can protect the brain from Alzheimer's disease. In individuals with Alzheimer's disease, a peptide known as amyloid-β accumulates and forms tangled plaques.

Researchers have found that end-stage renal disease (ESRD) is much more prevalent in patients with slowly progressive type 1 ...

Results of the study at four weeks after cell transplantation demonstrate the survival and function of pancreatic beta cells as measured by the presence of circulating C-peptide, a biomarker ...

Researchers at IISc Bengaluru discover potential drug-free treatment for diabetes by enhancing beta-cell function with small ...

More information: Esra Karakose et al, Cycling alpha cells in regenerative drug-treated human pancreatic islets may serve as key beta cell progenitors, Cell Reports Medicine (2024). DOI: 10.1016/j ...