These processes are genetically controlled and depend both on the history of cells (lineage) and on the activities of signalling pathways, which coordinate the cell interactions leading to ...

One of the best studied signalling routes is the mitogen activated protein (MAP) kinase signal transduction pathway which plays a crucial role in many aspects of immune mediated inflammatory responses ...

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license. This work is licensed under a Creative Commons Attribution 4.0 International ...

Liver fibrosis and its end stage, liver cirrhosis, is the final common pathway of chronic liver diseases ... The initiation phase of HSC activation is due to paracrine stimuli from injured neighboring ...

The study revealed that light input pathways influence clock neurons ... that clock neurons communicate through peptidergic paracrine signaling. These findings significantly improved our ...

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Three very important feasts and the pattern of the Tabernacle and the Ark of the Covenant — all symbolic of Christ and His relationship with believers today. And let them make Me a Sanctuary; that I ...

Department of Medicine, Division of Engineering in Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States Wyss Institute for Biologically Inspired ...

Conclusions We describe here a novel mechanism of action of HCQ, that is, interference with the assembly of endosomal NOX2. Since endosomal NOX2 is involved in many inflammatory and prothrombotic ...