Cerebellar degeneration occurs when the neurons in the cerebellum deteriorate. The cerebellum is the portion of the brain that controls balance and muscle coordination. A number of conditions can ...

For example, subacute cerebellar ataxia in the setting of ovarian cancer is sufficiently characteristic to be called paraneoplastic cerebellar degeneration, as long as other causes have been ruled out ...

The remaining three patients were lost to follow-up. TRIM46-IgG is a biomarker of paraneoplastic neurological autoimmunity. The neurological phenotypes were diverse but restricted to the CNS, as ...

Several neuropsychiatric disorders such as attention deficit-hyperactivity disorder (ADHD), autism spectrum disorder (ASD), as well as neurological diseases such as spinocerebellar ataxia type 3 (SCA3 ...

Fibroid degeneration occurs when a uterine fibroid outgrows its limited blood supply and begins to die. Fibroids are benign uterine growths made of smooth muscle cells and fibrous tissue. Some people ...

Macular degeneration is very common and affects an estimated 19.8 million people in the United States. Approximately one in 10 Americans age 50 and older have an early form of the disease and as many ...

Oligodendroglial myelin sheaths can be affected leading to axonal degeneration. Astrocytosis leads to reduced blood–brain barrier ... The most striking evidence is provided by tumor-associated ...

Macular degeneration usually refers to the age-related degenerative changes in the retina that can result in loss of central vision. It is caused by abnormal blood vessel growth (a condition ...

Using a unique cerebellar disruption approach in non-human primates, this study provides valuable new insight into how cerebellar inputs to the motor cortex contribute to reaching. Evidence for many ...

A new study from Karolinska Institutet and Mayo Clinic has revealed important insights into brain degeneration in dementia with Lewy bodies (DLB). This research, published in JAMA Neurology ...

Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries. Nature Genetics , 2024; 56 (12): 2659 DOI: 10.1038/s41588-024-01764 ...