This fundamental work presents two clinically relevant BMP4 mutations that contribute to vertebrate development. The convincing evidence supports that the site-specific cleavage at the BMP4 pro-domain ...

What is ALPK2, and how can it help treat heart failure? Researchers have found that this heart-specific enzyme may prevent ...

The study also explored the impact of PDK1 Y163 phosphorylation on lung cancer cell proliferation, invasion, and metabolism. It was found that a phospho-dead mutation at Y163 abolished the ...

Driver mutations are the pathophysiological hallmark of the disease, but the role of mutation clearance after transplantation is unclear. In patients with myelofibrosis, clearance of driver ...

In early December 2024, a group of researchers published an article in the journal Science, entitled "A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors".

Jan. 23, 2025 — Researchers have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some ...

Researchers in the group of Dr. Myriam Charpentier discovered a mutation in a gene in the legume Medicago truncatula that reprograms the signaling capacity of the plant so that it enhances ...