We see color because photoreceptor cones in our eyes detect light waves corresponding to red, green, and blue, while dimness or brightness is detected by photoreceptor rods. Many non-mammalian ...
A type of pineal photoreceptor cell that contains a protein called parapinopsin 1 (PP1) detects color. These PP1 cells become active and inactive in proportion to the difference in wavelength of ...
Inherited retinal diseases (IRDs) are a group of monogenic disorders caused by mutations in more than 280 genes, and are characterized by progressive degeneration of photoreceptor cells in the retina.
Researchers uncovered how zebrafish detect colors using photoreceptor cells in the pineal gland. The protein parapinopsin 1 (PP1) is inactivated by arrestin proteins Sagb and Arr3a, which switch roles ...
Two new compounds may be able to treat retinitis pigmentosa, a group of inherited eye diseases that cause blindness. The compounds were identified using a virtual screening approach.
The companies will work together by using the codon-optimized BBS1 AAV9 vector to minimize the vision loss caused by the ...
Axovia’s lead program AXV101 is an adeno-associated virus (AAV9)-based investigational gene therapy that aims to slow down or ...
Lineage Cell Therapeutics, Inc.’s LCTX share price has surged by 14.78%, which has investors questioning if this is right time to sell.
This study identifies small molecule pharmacochaperones that suppress the pathogenic effects of various rhodopsin mutants in vitro and slow photoreceptor cell death in a mouse model of RP ...