Recombination events in many organisms are concentrated in highly localized areas termed 'hot spots'. Hot spots can be detected by statistical analysis of genetic variation, analysis of pedigrees ...

Ltd (China). We constructed a BATF-shRNA plasmid by using the PLKO.1-TRC cloning vector as the empty plasmid. Plasmid recombination was utilised to generate the BATF plasmid with some specified ...

Since its founding in 1996, the company has published seven major studies on gene recombination. While the Human Genome Project, completed in 2003, mapped our DNA, many questions about how human ...

One reason is the fact that much research related to ovarian cancer has focused on strategies combining chemotherapy with ...

While this shuffling, known as recombination, is essential for genetic diversity, errors in the process can lead to serious reproductive issues. These failures can result in genetic errors that ...

multicopy plasmid or a small portion to a recipient cell, where these genetic elements insert into the chromosome or replicate independently if compatible with the inhabitant plasmids. Integrons use ...

Homologous recombination is the exchange of DNA strands of similar or identical nucleotide sequence. It can be used to direct error-free repair of double-strand DNA breaks and generates sequence ...

In this valuable manuscript, authors ablate cerebellar oligodendrocytes during postnatal development and show that synchrony of calcium transients in Purkinje neurons and behaviours are affected even ...

Aspiring participants of the GATE 2025 Biotechnology (BT) exam must go through the syllabus of Biotechnology (BT). The ...

Immunizing the host with a piece of viral DNA rather than an antigenic protein fragment of the virus, helps to stimulate the generation of cell-mediated immunity (Fig. 2). DNA vaccines contain the ...