Here, we use a synthetic amphiphile to modulate the membrane mechanical properties of cell-derived vesicles and probe channel activation. Using precise membrane mechanical characterization approaches ...

A research team from POSTECH has developed a biodegradable polymer-based delivery system that efficiently transports mRNA.

By modifying existing polyanionic polymers to become electroneutral, researchers were able to extract proteins and lipids from membranes without the complications caused by high charge densities.

Researchers outline their improved lipid-polymer nanoparticle for holding mRNA that is stable when nebulized and successfully delivers aerosols (liquid droplets) in mice's lungs. mRNA medicines ...