Nurix Therapeutics, Inc. stock slid 40% after promising NX-5948 results in CLL. NX-5948 shows efficacy in heavily pre-treated ...

Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, protein quality control and cellular health, whose failure could be the leading ...

A research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating ...

Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, protein quality control and cellular health, whose failure could be the leading ...

Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, ...

Researchers from Cologne, Bochum, Padova and Angers have discovered a novel connection between mitochondrial function, protein quality control and ...

A new study has identified an enzyme that plays an important role in breaking down unneeded or damaged proteins in the heart -- an important process for maintaining heart health.

A new study has identified an enzyme that plays an important role in breaking down unneeded or damaged proteins in the heart – an important process for maintaining heart health.

The ubiquitin-proteasome system (UPS) is a non-lysosomal proteolytic pathway involved in numerous normal functions of the nervous system, modulation of neurotransmitter release, synaptic plasticity, ...

This occurs through interactions with the protein FBXO31. On binding CTAPs, FBXO31 summons a ubiquitin ligase to tag the modified proteins for dismantling by the proteasome. Curiously, loss of FBXO31 ...

As a PhD student, his work was investigating the regulation, function, and molecular mechanism of action of AMPK-related NUAK1 ... During that time his research was focused on the role of DYRK2 as a ...