Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...
serotonin and dopamine secretion, blood pressure, muscle regeneration, bone remodeling, bronchodilation, kidney function and many other physiological pathways. The Olfactive Biosolutions team has deep ...
Our understanding of the hepatitis C virus (HCV) life cycle and protein function at the molecular level has provided multiple targets for the development of direct acting antivirals (DAAs).
Proteins created by cells often are not used by the cell that synthesised them. These proteins go through the protein secretory pathway and are, as the name suggests, secreted out of the cell. This ...
Activation of the hexosamine pathway resulted in significant deterioration of glucose-stimulated insulin secretion along with ... and increased uncoupling proteins, leading to the opening of ...
Proteinuria is the presence of too much protein in the urine. It is typically a sign of kidney disease, often in people diagnosed with diabetes, but also can occur with pregnancy, lupus, and other ...
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Years later, it was replaced with exciting-looking “low carb” claims. These days, “high in protein” is a benefit you’ll see touted on lots of products, whether they’re protein powder, bone broth, ...