Multiple Sequence Alignment (MSA) is a fundamental technique in bioinformatics that aligns three or more biological sequences, such as DNA, RNA, or protein sequences. This alignment helps ...

A tool for automated alignment trimming in large-scale phylogenetic analyses. Development version: 2.0 ...

GA2Vec leverages vector embeddings of protein sequences from ProtBERT, ESM-2, and ProtT5-XL-UniRef50 to reconstruct ... The genetic algorithm optimizes network alignment by refining these clusters ...

Protein sequence analysis is a crucial area ... amino acid occurring at each position in a sequence, often used in sequence alignment and motif discovery. This Nature Research Intelligence Topic ...

Alignment based methods include building blocks of alignments and matching unknown protein sequences against these blocks to correlate many connections at once. The method of protein classification by ...

ProTrek delivers transformative improvements, particularly in protein sequence-function retrieval, achieving 30-60 times the performance of previous methods. It also surpasses traditional alignment ...

Experiments demonstrate that our TaxDiff achieves state-of-the-art results in both taxonomic-guided controllable and unconditional protein sequence generation, excelling in structural modeling scores ...

For the first time, researchers used data from protein shapes and combined it with data from genomic sequences to improve the reliability of evolutionary trees—which they describe as a critical ...

Proteins, essential macromolecules for biological processes like metabolism and immune response, follow the sequence-structure-function paradigm, where amino acid sequences determine 3D structures and ...

The model also learns about the nature of things while being tried on massive banks of data. The ESM3 model was trained in 771 billion tokens, which were in turn generated from 3.15 billion protein ...

After a few weeks of forcing herself to eat chicken breast and cottage cheese late in the evening despite not being the least bit hungry, Michelle Wilkes, 59, realized that counting protein grams ...

Some proteins find their 'soulmate' at birth Date: January 27, 2025 Source: Université de Genève Summary: Proteins, the pillars of cellular function, often assemble into 'complexes' to fulfill ...