Protein sequence analysis is a crucial area of bioinformatics that focuses on understanding the structure and function of proteins based on their amino acid sequences. Recent advancements in ...

An artificial intelligence model has created a new protein that researchers say would have taken 500 million years to evolve ...

Adhesion G protein-coupled receptors (GPCRs) are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for ...

Symptoms of Huntington's disease appear late in life. Research reveals how DNA repeats grow toxic over time, explaining the ...

Scientists at the Faculty of Medicine have now developed an innovative numbering system for the GAIN domain, a protein domain ...

where amino acid sequences determine 3D structures and functions. Computational protein science AIms to decode this relationship and design proteins with desired properties. Traditional AI models have ...

Adhesion G protein-coupled receptors are a large class of membrane proteins that detect chemical and mechanical stimuli in the body. The GAIN domain ...

Another significant resource is the UniProt Knowledgebase, which has expanded to include over 227 million protein sequences, complete with functional annotations. This database not only provides ...

Recent analysis of amino acid prevalence goes back to the theoretical common ancestors of life.

Rapid deployment of AI in scientific pursuits is creating an assembly line of discoveries that is revolutionising the world, ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements.