The building blocks of proteins are amino acids, which are small organic molecules ... side chains. The chemistry of amino acid side chains is critical to protein structure because these side ...
To develop a small-molecule drug, researchers spend years combing through thousands of organic compounds ... But not all target proteins were receptive to this method, called structure-based ...
The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka ... "The key to understanding this family of proteins has been the determination of their molecular structure.