RNA vaccines are composed of the nucleic acid RNA, which encode antigen genes of an infectious agent. When administered to host cells, the RNA is translated into protein antigens that elicit ...

The team’s RNA-LNP approach – described in the journal Cell – works by reprogramming the TME using a sample of the tumour itself, so it can work both as a vaccine to stimulate an immune ...

A recent study published in Nature Communications by researchers at the National Institute of Allergy and Infectious Diseases (NIAID) and collaborators evaluated a replicating RNA (repRNA) vaccine ...

The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

For mRNA vaccine development, Oxford Nanopore sequencing has been modified to sequence them directly without reverse transcription. Although the accuracy of direct sequencing of RNA is lower than that ...

NTxscribe produces 10-50 mg of high integrity RNA in two hours, shortening timelines for bringing new therapies and vaccines to market and empowering researchers, biotech, and pharmaceutical ...

Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA. Researchers ...

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What’s more, DNA vaccines have potential side effects, including immune tolerance of the organism to the expressed antigen, chromosomal integration, and injection site inflammation (219). RNA vaccines ...