Kinases and phosphatases, which remove phosphate groups, are involved in nearly all signal transduction processes, often with cascades of phosphorylation events. Development of genetically encoded ...

Pro-inflammatory macrophage activation is a hallmark example of how mitochondria serve as signaling organelles. Oxidative phosphorylation sharply decreases upon classical macrophage activation, as ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Chloride ions are important inducers of salt ...

1 Department of Radiation Oncology, Inselspital, Bern University Hospital, Bern, Switzerland 2 Radiation Oncology, Department for BioMedical Research, University of Bern, Bern, Switzerland RAS ...

An antibody array is one of the simplest methods for measuring the relative levels of expression or phosphorylation of several proteins in a single sample. In this study, we present the successful and ...