Announcing a new article publication for BIO Integration journal. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in China in December 2019, rapidly spread worldwide, ...

For decades, lab-made antibodies have been used to support patients fighting specific diseases. These treatments have become a cornerstone of cancer therapy and were among the first medical solutions ...

Ubiquitin-binding domains (UBDs) are modular elements that ... including protein stability, receptor trafficking, DNA damage responses and inflammatory pathways. UBD preferences for distinct ...

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We successfully characterized the binding interactions of the native CXCL7 dimer to receptor N-domain and GAG heparin. These data indicated that the receptor interactions of the dimer are similar to ...

The strength of theoretical approaches is in the simplification of complex biological systems. We here consider the general problem of receptor–ligand binding in the context of antibody–antigen ...

Pharmaceutical ads are difficult to avoid in American television programming and a growing number of them promote a class of ...

Researchers at the Center for Life Sciences at the Paul Scherrer Institute PSI have for the first time identified structural ...

A newly developed vaccine against a group of viruses including SARS-CoV-2 is producing promising results in mice, part of the ...

The new virus was named by World Health Organization (WHO) as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the associated disease Coronavirus Disease-2019, also known as COVID-19.

Using liquid chromatography–tandem mass spectrometry, we identified VIM as a protein that binds to the SARS-CoV-2 spike (S) protein. We showed that the S-protein receptor binding domain (RBD) is ...